Henry is a precocious young boy, conceived in a petri-dish, raised by his single mother, Patricia, and is smarter than all of his peers. However, the one question he can't answer is, who is his father? Henry's attempts at locating his father lead him to Dr. Slavkin O'Hara, a university professor who has decided to raise his daughter, Audrey, as a psychology experiment in a world free of gender bias. Patricia starts fearing that she's losing her son, Audrey wishes she didn't have a father, Dr. O'Hara has no idea how to keep his daughter happy, and Henry may just have found the family he was looking for.

Sam (Shannon Elizabeth), a soon-to-be bride, faces a dilemma when an old college crush comes back into her life... Who will she choose?